Auteur Topic: 10 % Italiaanse coeliakiepatiŽnten eet niet glutenvrij  (gelezen 274 keer)

tine

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10 % Italiaanse coeliakiepatiŽnten eet niet glutenvrij
« Gepost op: december 27, 2020, 21:00:47 »
Van 223 Italiaanse volwassenen die gemiddeld 7 jaar weten dat ze coeliakie hebben, eet 90 % glutenvrij en 10 % niet. Aanvankelijk lag de dieettrouw iets lager, op 84 %, maar sommige patiŽnten besloten later toch om glutenvrij te gaan eten. CoeliakiepatiŽnten met klassieke klachten zoals diarree en gewichtsverlies eten meestal glutenvrij. Anderen met DH of een ijzertekort eten vaker gluten. Wie meteen vanaf het begin glutenvrij gaat eten, houdt dit meestal goed vol. 


Clin Gastroenterol Hepatol. 2020 Dec 15;S1542-3565(20)31672-4. doi: 10.1016/j.cgh.2020.12.015. Online ahead of print.
Determinants And Trends Of Adherence To A Gluten-Free Diet In Adult Celiac Patients On A Long-Term Follow-Up (2000-2020)
Annalisa Schiepatti 1, Stiliano Maimaris 2, Maria Luisa Nicolardi 2, Eleonora Alimenti 2, Marta Vernero 2, Martina Costetti 2, Stefania Costa 2, Federico Biagi 2

PMID: 33338656 DOI: 10.1016/j.cgh.2020.12.015

Background & aims: Data on factors governing long-term adherence to a gluten-free diet (GFD) in celiac disease (CD) are scarce. We aimed to determine trends and clinical predictors of long-term GFD adherence in adult CD.

Methods: Initial and long-term (>3 years) GFD adherence, clinical characteristics at baseline and follow-up were collected retrospectively from celiac patients followed-up over 20 years (2000-2020). Predictors of long-term GFD adherence at diagnosis, and follow-up were evaluated by multivariate logistic regression.

Results: 248 patients (37Ī12 years, 186F, median time on a GFD 90 months) were included. Twenty-five (10.1%) had only short-term follow-up (<3 years) while 223 (89.9%) had initial and long-term dietary assessment. 187/223 (83.9%) patients were initially adherent and 36/223 (16.1%) were not. 17/36 (47.2%) patients initially not adherent become adherent, while only 4/187 (2.1%) initially adherent patients became not adherent. In the long-term 200/223 (89.7%) were adherent and 21/223 (9.4%) patients were not. Adherence improved more frequently than worsened (OR 39.5, 95%CI 11.4-178.5, p<0.01). Classical symptoms (diarrhea,weight loss) at diagnosis of CD predicted stricter long-term GFD adherence (OR 3.27, 95%CI 1.21-8.81; p=0.02), while anemia (OR 0.31, 95%CI 0.12-0.82; p=0.02) and dermatitis herpetiformis (OR 0.23, 95%CI 0.06-0.91; p=0.04) predicted poorer long-term adherence. At follow-up, initial GFD adherence (OR 42.70, 95%CI 10.70-171.00; p=0.04) was the major determinant of long-term GFD adherence.

Conclusions: GFD adherence changes over time in <10% of patients, generally improving when it does. Major determinants of long-term GFD adherence are classical symptoms at diagnosis and initial adherence to a GFD. Patients with anemia or dermatitis herpetiformis at diagnosis require stricter dietetic input.


Mijn zoon (21) en ik eten allebei glutenvrij. Wij zijn extreem gevoelig voor sporen van gluten (via besmetting, tarwe-derivaten en hulpstoffen). Ik ben wetenschapsredacteur voor het Glutenvrij Magazine van de NCV.