Auteur Topic: Ook paarden en pony's kunnen last hebben van gluten  (gelezen 702 keer)

tine

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Ook paarden en pony's kunnen last hebben van gluten
« Gepost op: augustus 28, 2020, 23:36:43 »
Ergens in Nederland loopt een 11-jarig sportpaard in de wei dat geen stro of ander voedsel met gluten meer krijgt. De reden: het paard heeft last van gluten. Er zijn paarden en pony's bij wie de dunne darm beschadigd raakt door gluten. Bij dit paard raakte ook de huid beschadigd. Dat is niet eerder beschreven in de medische literatuur over ziekten bij paarden. Het in coeliakie gespecialiseerde Amsterdam UMC hielp dierenartsen met de diagnostiek bij het paard. Ook 40 pony's werden getest op coeliakie. Eentje had ook verhoogde coeliakie antistoffen in het bloed.
 

Preliminary Notes on Equine Tissue Transglutaminase Serology and A Case of Equine Gluten-Sensitive Enteropathy and Dermatitis in an 11-Year-Old Dutch Warmblood Horse
Rickvan Proosdija ChrisMulderb MartineReijmc HettyBontkesc Maryvon BlombergcH anvan der Kolkde
https://doi.org/10.1016/j.jevs.2020.102999

Highlights

Gluten may play a role in equine inflammatory small bowel disease.


This is the first study assessing transglutaminase antibodies in sera from healthy ponies and showing a correlation with age.


The presented case is possibly the first one of a horse with gluten-sensitive enteropathy and dermatitis


Abstract
It has been suggested that gluten may play a role in equine inflammatory small bowel disease (ISBD). Previous work showed an association between equine gluten-sensitive enteropathy and IgA antibodies to tissue transglutaminase (TGA) in serum. The purpose of this study is to investigate the prevalence of IgA antibodies to TGA in a group of healthy non–gluten-free sport ponies and to present a case of tentative gluten-sensitive enteropathy and dermatitis in a horse. Blood samples were obtained from 40 healthy jumping ponies. The ponies comprised 12 mares, 8 stallions, and 20 geldings with an average age of 9.0 ± 3.8 years (±SD; range 3–19 years). Sera were tested for IgA antibodies against human recombinant TGA. Significance (P < .05) of the correlation between TGA titer and age in these ponies was assessed using Pearson test (two tailed). In addition, to further illustrate tentative equine gluten-sensitive enteropathy and dermatitis, the clinical course in an 11-year-old Dutch Warmblood sport horse gelding has been described. The average TGA titer was 21.4 ± 13.6 AU/mL (range 2–65 AU/mL). There was a significant (P = .013) correlation (r = 0.389) between age and TGA titer in ponies. One of the 40 ponies (2.5%) showed an elevated TGA titer. An elevated TGA titer decreased after a gluten-free ration for 3 months in an 11-year-old Warmblood gelding with a tentative diagnosis of ISBD associated with full remission of the generalized skin reaction. To our best knowledge, this is the first study assessing TGA antibodies in sera from healthy non–gluten-free ponies and showing a correlation with age. The presented case could be the first one of a horse with a tentative diagnosis of gluten-sensitive enteropathy combined with dermatitis. Given the reported findings, this study warrants further investigations into gluten-sensitive enteropathy and dermatitis in individual horses affected with ISBD.

Mijn zoon (20) en ik eten allebei glutenvrij. Wij zijn extreem gevoelig voor sporen van gluten (via besmetting, tarwe-derivaten en hulpstoffen). Ik ben wetenschapsredacteur voor het Glutenvrij Magazine van de NCV.