Auteur Topic: Vitiligo (huidziekte met witte vlekken) en coeliakie gaan soms samen  (gelezen 381 keer)

tine

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Vitiligo (huidziekte met witte vlekken) en coeliakie gaan soms samen
« Gepost op: oktober 09, 2019, 17:29:21 »
Duitse huidartsen willen patiŽnten met vitiligo (witte vlekken op hun huid door pigmentverlies) testen op coeliakie. PatiŽnten met vitiligo hebben namelijk een grotere kans op coeliakie. Ook zien de artsen het nut van een Ďproefdieetí zonder gluten voor mensen met vitiligo, om te testen of hierdoor de witte vlekken op de huid verdwijnen. 

Hautarzt. 2019 Oct 4. doi: 10.1007/s00105-019-04482-5. [Epub ahead of print]
[Prevalence of an association between coeliac disease and vitiligo].
[Article in German]
Henker J1, Hartmann A2.

Coeliac disease and vitiligo are immune-mediated disorders that are often associated with other immune-mediated disorders. In a prospective study we included 174 patients with vitiligo between the ages of 3 and 79 years (mean 38.2 years) to investigate whether there is an increased risk for coeliac disease in patients with vitiligo. We determined immunoglobulin A and IgA- and IgG-antibodies against tissue transglutaminase, while also optionally measuring blood count, ferritin, and endomysial-IgA-antibodies. In 3 of 174 (1.7%) vitiligo patients, coeliac disease was diagnosed serologically and by duodenal biopsy. Assuming a coeliac disease prevalence of less than 0.0033%, the incidence is statistically significant. In two other patients with vitiligo, coeliac disease was already known and confirmed with biopsy. If these two patients are included in the calculation, 2.8% (5 von 176) of vitiligo patients have coeliac disease. This value is statistically significant even with a higher coeliac disease prevalence of 0.01. Thus, it is recommended that celiac-disease-specific antibodies also be determined during routine blood workup in vitiligo patients. In case of positive results, a gastroduodenoscopy with biopsy of the small intestine is recommended for diagnosis confirmation. If celiac disease is unlikely, a trial of gluten-free diet for a specific time should nevertheless be discussed with individuals affected by vitiligo because repigmentation appears possible.

PMID: 31584112 DOI: 10.1007/s00105-019-04482-5
Mijn zoon (19) en ik eten allebei glutenvrij. Wij zijn extreem gevoelig voor sporen van gluten (via besmetting, tarwe-derivaten en hulpstoffen). Ik ben wetenschapsredacteur voor het Glutenvrij Magazine van de NCV.