Auteur Topic: ESPGHAN guidelines diagnosis coeliac disease children/adolescents  (gelezen 2677 keer)

ine

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ESPGHAN guidelines diagnosis coeliac disease children/adolescents
« Gepost op: januari 23, 2011, 16:38:48 »
Van het Celiac Disease Consortium


ESPGHAN guidelines diagnosis
coeliac disease children/adolescents


An evidence-based approach
CDC 11 November 2010

ML Mearin


Een paar stukjes
High serum anti-TG2 antibodies predict CD
Marsh II-III lesions

High serum anti-TG2 antibodies predict CD
with Marsh II-III lesions

Can histology be predicted by antibodies? Recommendation
Histological assessment might be omitted in cases with
• symptoms that can be referred to CD
• high IgA anti-tTG levels > 10x upper normal limit, verified by EMA positivity
• HLA DQ2 and/or DQ8 positive

Child with symptoms of CD

Consequences new ESPGHAN diagnostic criteria CD
• Patients
• Physicians
• Patients interests groups
• Researchers
• Epidemiologists, dieticians, gluten-free producers, antibody
  detection industry……

Consequences new ESPGHAN diagnostic criteria CD in Netherland
Role for CDC???


Gehele artikel:
http://www.celiac-disease-consortium.nl/attachments/080_Mearin%20ESPGHAN%20CD%20WG%20voor%20CDC%20november%202010.pdf







Groeten, Ine